Caltech Division of Biology and
Biological Engineering
Bi 122 · Genetics

Syllabus

Course description

Bi 122. Genetics. 9 units (3-0-6); first term. Prerequisites: Bi 8 or Bi 9, or instructor's permission. Lecture and discussion course covering basic principles of genetics. Not open to freshmen. Instructors: Hay, Staff.

Welcome to Bi 122! This course covers a broad range of topics in genetics, from the classic experiments of Mendel to the modern sciences of gene regulation and genomics.

Lectures are usually supplemented with handouts summarizing the material covered. Because a good deal of what is presented in class does not appear in the book, it is worth attending at least a few of the lectures.

Recommended text
An Introduction to Genetic Analysis
A. J. F. Griffiths et al. · 12th edition
W. H. Freeman and Company
ISBN 978-1-319-28646-0

Chapters 7–9 should be reviewed, skimmed for terms and general sense, if you have not taken Bi 8. If you are unsure of your mastery of the Bi 8/9 material, or came from another department or school without an equivalent course, read those chapters. For some parts of the course the book does not provide adequate information, or presents it with a slant different from what is covered in class.

Problem sets and grading

Problem sets are released on Friday and due the following Thursday at 11:59 pm.

Sets less than 24 hours late lose 10% of the grade; up to 48 hours late, 20%. In general they should not be handed in later than that. Sets are graded from 0 to 100%, the lowest score is discarded, and the remaining seven count equally toward 60% of the final grade.

A 91–100% B 81–90% C 71–80% D 65–70% F < 65%

If a test turns out much harder than intended, the conversion may be shifted so that a score lower than 91% counts as an A, and so on; any such change is announced. It is never shifted the other way. Under any circumstances a 91% is an A.

Collaboration policy

Problem sets. You must work completely independently on each problem set for three hours. After that you are free to discuss the problems, and may use visual aids, the digital equivalent of chalkboards, marker boards, or scratch paper.

You may not use another student's answer to any problem when it is in its final form, ready to submit. You must write up your solutions independently of others, and not use any recorded notes of discussion sessions. There is to be no division of effort.

Exams. No collaboration, either verbal or written. Personal calculators are permitted. Each exam counts for a fifth of the final grade.

Due dates
ItemDue TimeFormat
Problem Set 1Thu, Oct 811:59 pm
Problem Set 2Thu, Oct 1511:59 pm
Problem Set 3Thu, Oct 2211:59 pm
Problem Set 4Thu, Oct 2911:59 pm
Midterm ExamTBD TBDIn person
Problem Set 5Thu, Nov 1211:59 pm
Problem Set 6Thu, Nov 1911:59 pm
Problem Set 7Thu, Nov 2611:59 pm
Problem Set 8Thu, Dec 311:59 pm
Final ExamTue, Dec 8 3:30–6:30 pmIn person
60%
Problem Sets
8 issued · best 7 counted
20%
Midterm
In person · open book
20%
Final
In person · open book
Extra credit

Presentation, up to 5%. Choose one topic from the list of paper options, then pick an open class date on the sign up sheet. Professor Hay gives a brief introduction and acts as MC, then you present for 10 to 20 minutes during the last 20 minutes of that class. See presentations for details.

CTLO science nights, 6%. Outreach in collaboration with the CCID (Caltech Center for Inclusion and Diversity), volunteering for a science night organized by Caltech's CTLO, earns 6% extra credit. Sign up ↗

If you can't make an exam

Email a TA or Professor Hay about being unable to take an exam, or about accommodations.

Make up exams and accommodations use the 12:15–3:15 pm block, on any day from Monday, Dec 7, through Friday, Dec 11.